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Category: Pregnancy Complications

Asked by danielsmommy

Q: Has anyone ever had or know anyone that has anti buffy antibodies?

I'm currently 13 wks pregnant and recently found out that i have anti buffy antibodies that i got from a blood transfusion after giving birth to my son 3 yrs ago. my titers are low as of now so my ob isn't worried he will check again next visit which is in 4 wks. if my titer levels start rising my ob will refer me to a high risk specialist that will monitor baby for signs of anemia weekly. I'm quite nervous about the outcome of this pregnancy. Worse case scenario my baby could die or have complications resulting in blood transfusions for baby while he/she is still inside me or after delivery. has anyone ever had this? What was the outcome did you go on to have a uneventful pregnancy and healthy baby? What are the chances of having serious complications? Help! One worried mama.

This question was asked Feb. 6, 2015 5:27am
Category: Pregnancy Complications

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Answers (1)

Answered by alcottadney - Jul. 10, 2015 10:03am
The Duffy glycoprotein is a receptor for chemicals that are secreted by blood cells during inflammation. It also happens to be a receptor for Plasmodium vivax, a parasite that invades red blood cells (RBCs) and causes malaria. RBCs that lack the Duffy antigens are relatively resistant to invasion by P. vivax. This has influenced the variation in Duffy blood types seen in populations where malaria is common. Hemolytic disease of the newborn (HDN) used to be a major cause of fetal loss and death among newborn babies. The first description of HDN is thought to be in 1609 by a French midwife who delivered twins—one baby was swollen and died soon after birth, the other baby developed jaundice and died several days later. For the next 300 years, many similar cases were described in which newborns failed to survive.
http://www.mommyliciousmaternity.com/

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